Recommendations for management of low platelets even after transfusion: 1. transfuse single-access (filtered leukocytes) and antigen-negative (reduced immune neutralization) platelets as much as possible. 2. Perform platelet cross-matching and HLA matching (reduce transfusion of incompatible platelets). 3. Aggressive treatment of the primary disease (platelets recover slowly when the primary disease resolves). Platelet transfusion is often used as a treatment plan to raise platelets urgently, and the effect is obvious in most cases. It is also very common that platelets are still low even after transfusion, which may be due to ineffective platelet transfusion, and the preventive measure is mainly to transfuse according to platelet mating. For patients with repeated transfusion needs, it is recommended to test for HLA and HPA-related antibodies before transfusion therapy, and if there are no conditions to test for antibodies, hormones can be given to protect platelets before platelet transfusion.