Frequent nosebleeds are not necessarily a precursor to leukemia, but can also be caused by problems with the nasal cavity itself, such as dryness and erosion of the nasal mucosa and nasal hemangioma. Leukemia is a class of malignant clonal diseases of hematopoietic stem cells. Early symptoms include pallor, depression, malaise, loss of appetite, nasal or gum bleeding, etc. Fever and bone and joint pain similar to rheumatic fever are the first symptoms in a few children. However, dryness of nasal mucosa, congestion and breakage of the lee area, nose picking, nose digging, nasopharyngeal tumor, etc. can also cause nosebleeds and need to be seen in the hematology department or ENT department of the hospital to determine the cause. Therefore, frequent nosebleeds are not a specific manifestation of leukemia. If leukemia is diagnosed, comprehensive treatment, mainly chemotherapy, is required, then treatment at the hematology department is needed, and symptomatic treatment can be given according to the situation when combined with nosebleeds.