The diagnosis of optic nerve atrophy is generally based on three main considerations: first, to see whether there is a decrease in visual acuity and visual field or defects. If optic nerve atrophy is present, there is usually a significant loss of visual acuity and visual field defects. Second, it depends on the results of the examination. Optic nerve fiber layer analysis can be performed to clarify whether the optic nerve fiber layer has thinned, because optic nerve atrophy is usually due to various causes of damage to the optic nerve tissue, in which case the optic nerve tissue will become very thin, which is also essential for the diagnosis of optic nerve atrophy. Thirdly, the performance of the optic disc is the main factor. After the occurrence of optic nerve atrophy, the color of the optic disc will become pale, and the cup-to-disc ratio is usually larger, over 0.6 or 0.8.