The death of Steve Jobs has sounded a health alarm for people: pancreatic cancer is a kind of “lifestyle cancer”, we should change our bad lifestyle and actively prevent pancreatic cancer from happening. Warning 1: Pancreatic cancer has a high mortality rate Pancreatic cancer is an extremely dangerous malignant tumor, although about 1 in 20,000 people in China has pancreatic cancer, but the disease develops quickly and has a high mortality rate. The National Institutes of Health reported that the 1-year survival rate of pancreatic cancer is 8% and the 5-year survival rate is 3%. Our statistics show that the 5-year survival rate is only about 5%. In recent years, the incidence of pancreatic cancer in the United States has increased 3 times in 10 years, with 43,140 new cases and 36,800 deaths in 2010, ranking tenth in incidence and fourth in mortality rate of malignant tumors. The increasing trend of pancreatic cancer incidence and death in China is very significant, with the incidence rate increasing about 6 times in the past 20 years. According to the 2007 tumor registry data from 38 registries nationwide, pancreatic cancer ranks 7th in incidence and 6th in death rate of malignant tumors. Alert 2: Poor lifestyle may be the “trigger” Currently, in addition to the increasing number of elderly people in China, with the significant improvement in living conditions, some risk factors associated with pancreatic cancer, such as smoking, chronic pancreatitis, obesity, diabetes and even lack of exercise, all have a role in promoting the development of pancreatic cancer. Studies have shown that the correlation between smoking and the development of pancreatic cancer is the most significant, and the trend of pancreatic cancer is closely related to changes in the population of smokers; various chronic pancreatitis, including alcoholic, non-alcoholic, hereditary and tropical pancreatitis, are associated with pancreatic cancer to some extent; diabetes may be a factor in the development of pancreatic cancer; dietary factors are also related to the development of pancreatic cancer, and some studies have shown that excessive Dietary factors are also related to the development of pancreatic cancer, and some studies have shown that excessive sweets and high-fat diet may be related to the development of pancreatic cancer. Genetic susceptibility is also associated with pancreatic cancer. Therefore, controlling smoking, eating a balanced diet, increasing the intake of fresh fruits and vegetables, maintaining a normal weight, preventing diabetes and chronic pancreatitis can reduce the risk of pancreatic cancer to a certain extent. Warning 3: Most of the pancreatic cancer is already in the middle and late stages when it is found. Pancreatic cancer is insidious in origin, the pancreas grows in the posterior peritoneal cavity, and there are no obvious symptoms in the early stage. It is the lowest among all cancers. The early detection rate of pancreatic cancer is only 5-7% in China, the lowest among all cancers. Almost once diagnosed, patients are in the middle and late stages, and only about 20% of them have the hope of radical surgery. Most patients with pancreatic cancer will experience weight loss, abdominal pain, jaundice, poor appetite, etc. About half of the patients will experience upper abdominal discomfort, bloating and fatigue, and about 20% of the patients will have back pain, diarrhea and black stool. The main symptoms of early stage patients are upper abdominal discomfort, poor appetite, abdominal distension and weakness. Once weight loss, abdominal pain and jaundice occur, it indicates that it may be in the middle or late stage. Therefore, people should be vigilant, especially the high-risk groups, including patients with acute and chronic pancreatitis, family history of pancreatic cancer, hereditary pancreatitis, long-term smokers and newly discovered diabetics, should be closely observed and followed up in time, and strive for early detection and diagnosis and treatment. Alert 4: Change bad habits to prevent the disease before it happens Pancreatic cancer is a “lifestyle cancer”. The rapid growth of pancreatic cancer is related to the improvement of living conditions and poor life style, therefore, the first thing is to have a healthy lifestyle, early intervention and maintenance of health, and to change unreasonable habits. The diet should avoid high-fat meals, and should ensure a reasonable mix of meat, eggs, vegetables, fruits and grains in the diet, and increase the intake of coarse grains and vegetables and fruits appropriately. Furthermore, we should stay away from tobacco, which contains many carcinogenic substances that can increase the risk of pancreatic cancer. The risk of pancreatic cancer in smokers is 2 to 2.5 times higher than that in non-smokers, and the age of onset is 10 to 15 years earlier. In addition, alcohol abuse and overeating, the main factors of pancreatic cancer, should be avoided to avoid the long-term stimulation of chronic inflammation of the pancreas to increase the risk of cancer; weight should also be strictly controlled to avoid obesity, adhere to moderate physical activity, maintain a good mood, regular health check-ups, prevention before it is too late. It is worth noting that about 1/3 of chronic pancreatitis may be transformed into pancreatic cancer, and pancreatic cancer is a dangerous disease that is becoming younger, especially among successful people and CEOs. Among the nearly 1,000 cases of pancreatic cancer that we have treated clinically, about 30% are entrepreneurs, bosses and top managers, while liver cancer, intestinal cancer and other cancers are far less concentrated. This has a lot to do with the high mental stress and socializing of top managers. Nowadays, the peak age of pancreatic cancer incidence has advanced by nearly 20 years, from an average of 60 years old 10 years ago to about 40 years old now. A word of advice: People who are older than 40 years old, smokers and have a history of heavy alcohol consumption should not ignore pancreatic examination if they have non-specific discomfort in the upper abdomen, and should be highly alert to pancreatic cancer!