Gallbladder stones, a disease in which stones occur in the gallbladder, is a common disease in China, with an increased incidence with age and a higher incidence in women than in men. The main symptom of gallbladder stones is recurrent epigastric pain, which seriously affects people’s work and life. Gallstones are also one of the important causes of acute pancreatitis, which accounts for more than 80% of acute pancreatitis caused by gallstones in China. In addition, gallbladder stones have the possibility of gallbladder cancer if left untreated. Duan Shaobin, Department of Surgery, Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine The most reliable and effective treatment for gallbladder stones is cholecystectomy, which is basically performed laparoscopically nowadays. Laparoscopic cholecystectomy is generally performed by making four holes in the abdomen, i.e. a 1.2-1.5 cm incision in the umbilicus and three 0.5-1.0 cm incisions in the upper abdomen, through which small holes special instruments are placed to complete the gallbladder removal. Laparoscopic cholecystectomy is a new technology developed in modern minimally invasive surgery in the past 10 years or so. Compared with traditional open cholecystectomy, it can remove the lesion while maintaining an aesthetic body, and has the advantages of less surgical trauma, less interference with organ function, less patient pain, shorter hospital stay and faster return to normal activities. Laparoscopic cholecystectomy has become the best treatment for benign surgical diseases of the gallbladder that is popular among patients and recognized both at home and abroad. Although laparoscopic cholecystectomy is already a minimally invasive surgery, there are still 4 holes in the abdominal wall and 4 scars will remain after healing. Recently, with the rapid development of laparoscopic technology and related instruments and equipment, many scholars have attempted to further reduce the scarring of the abdominal wall while completing the surgery, and the world’s first transumbilical single-hole laparoscopic cholecystectomy was performed in the United States in May 2007, and several large hospitals in China have already performed this procedure. Transumbilical single-hole laparoscopic cholecystectomy, that is, only one hole is made in the umbilicus to complete the cholecystectomy, the most important feature of this operation is that there is only one 1.5cm hole and it is in the umbilicus, and after the hole heals, there is almost no trace of the operation due to the cover of the natural depression of the umbilicus. Moreover, it is clinically found that single-hole laparoscopic cholecystectomy through the umbilicus is less painful and faster to recover than four-hole laparoscopic cholecystectomy. Minimizing patient trauma is the eternal pursuit of surgeons, and this procedure may gradually increase with the gradual development of laparoscopic techniques as patients’ health and aesthetic requirements become higher. Single-port laparoscopic cholecystectomy through the umbilicus is a difficult operation because there is only one hole. It is only on the basis of the successful completion of more than 10,000 laparoscopic cholecystectomies that we have developed this new and advanced procedure. Therefore, this procedure should be performed in hospitals that are already very skilled in performing 4-hole laparoscopic cholecystectomies and are in a position to do so, and cases should also be selected according to the patient’s condition and the patient’s own aesthetic requirements.