Intestinal submucosal elevation with smooth surface consider the presence of intestinal smooth muscle tumor, colorectal cancer and other diseases, need to be under the guidance of the doctor for targeted treatment, such as drug treatment, surgical treatment, etc.. 1. Intestinal smooth muscle tumor: if the smooth muscle tumor is relatively small and there is no obvious obstruction symptom, it can be observed for the time being and rechecked regularly. If constipation and other symptoms occur, local surgery can be performed to remove it, and the prognosis is better. 2. Colorectal cancer: Early stage patients can undergo radical surgical resection, if the surgery can not be completely removed, chemotherapy drugs such as oxaliplatin, fluorouracil, etc., or radiotherapy, targeted therapy, etc. should be used. It is recommended to go to the hospital for consultation if there is a case of intestinal submucosal elevation with smooth surface, so as to ask the doctor to make judgment and clarify the cause of the disease.