Poor sleep that always wakes up in the middle of the night may be caused by depression, or it may be neurasthenia, which is also seen in menopause. Depression is a mental disorder disease in which patients show disinterest in anything, low mood, reduced self-evaluation ability, lack of confidence in life, and in severe cases, may have the desire to live lightly, and patients can also have sleep disorders. The main manifestation is easy to wake up early during sleep, and may also appear to dream more during sleep. It can be treated with oral citalopram, mirtazapine, or Dexedrine. If the patient is caused by menopause, it mostly occurs in women aged 45-55. The disease is mainly treated with oral meditation oral solution, Mrs. oral solution, and also with oral glutamate. The patient presents with more sweating, may have palpitations, chest tightness, shortness of breath, and may also have sleep disorders, difficulty in falling asleep, easy to wake up early during sleep, and more dreams during sleep.