In most cases, hypoglycemia testing does not require fasting and can be done at any time it occurs. When hypoglycemia occurs, if there is a blood glucose meter around, it should be tested immediately, and the blood glucose test and meal can be carried out at the same time. If there is no blood glucose meter at hand, oral food or first aid measures should be taken first to correct the patient’s symptoms of hypoglycemia, so as not to aggravate the symptoms of hypoglycemia or cause hypoglycemic coma while waiting for a blood glucose meter, which may endanger the patient’s life. However, when insulinoma is suspected and a starvation test is performed, hospitalization on an empty stomach is required for the test, and only beverages without calories and caffeine are allowed. Hypoglycemia generally refers to the concentration of glucose in the blood below 2.8 mmol/L. Most patients with blood glucose of 2.8-4.8 mmol/L are likely to have symptoms of sympathetic excitement, such as panic, sweating, hunger, flaccidity, and dizziness. In severe cases, there may also be disorders of consciousness, epilepsy, delirium, etc. Patients should be given glucose water, honey water, small snacks, and small cookie intake immediately to make the patient’s blood sugar rise as soon as possible. At the same time, measure the patient’s blood sugar and observe whether the patient’s discomfort symptoms improve. When hypoglycemia occurs, there is another more serious clinical symptom, which is damage to the central nervous system, such as the occurrence of hypoglycemic coma. When hypoglycemic coma occurs, no food should be fed because the patient is unconscious and choking and choking can easily occur after feeding food and endanger the patient’s life. If the presence of insulinoma is confirmed, surgical removal of the tumor is the preferred treatment. If surgery is not possible, medical treatment, such as the use of drugs such as octreotide and lanreotide, can be performed.