Hypoglycemia is the most common side effect that occurs in diabetic patients, especially elderly diabetic patients, during the application of hypoglycemic drug therapy. In mild cases, hypoglycemia can cause physical discomfort, while in severe cases, it can induce myocardial infarction, cerebrovascular accident, or even lead to coma and death. Hyperglycemia in diabetic patients, if the blood glucose is not particularly high, usually does not cause serious consequences in the short term, but if hypoglycemia occurs, it is likely to reach fatal consequences in a short time. Therefore, learning to self-identify hypoglycemia and dealing with hypoglycemia in a timely manner is especially important for our diabetic patients. So what is hypoglycemia? Under normal circumstances, our body can maintain blood glucose in a relatively constant range under neuroendocrine regulation. After meals, the body’s insulin secretion increases rapidly, so that the postprandial blood glucose does not rise too high, postprandial blood glucose stabilized at 4.4 ~ 7.8mmol / L; and in the state of starvation, the liver through glycogenolysis and gluconeogenesis to produce endogenous glucose, which makes the fasting blood glucose is not too low, and can be stabilized in the range of 3.9 ~ 6.1mmol / L. Therefore, the normal person neither hyperglycemia nor hypoglycemia. Generally speaking, when blood glucose is lower than 2.8mmol/L, it is called hypoglycemia. Diabetic patients in a long-term hyperglycemic state, blood sugar if the rapid decline in a short period of time, even if it does not reach 2.8mmol / L or less, there may be symptoms of hypoglycemia, we call this situation hypoglycemic reaction. So, what are the symptoms of hypoglycemia? And how to recognize hypoglycemia by these symptoms? Hypoglycemia is mainly manifested as two main types of symptoms, one is the symptom of sympathetic nervous system excitement: it is manifested as significant hunger, can’t wait to eat, weak limbs, trembling hands and feet, panic and dizziness, pale and cold sweating, and the blood pressure can be mildly elevated; the other is the symptom caused by the lack of sugar in the brain, and the light manifested as inattentiveness, slurred speech, slurred thinking, and unsteady walking. Some patients may show irritability and strange behavior. Severe hypoglycemia may lead to delirium, generalized cramps, and even coma and death. Elderly diabetic patients react poorly, symptoms of sympathetic nervous system excitement such as panic and cold sweat are often not obvious, and hypoglycemia is not easy to be detected, especially at night when hypoglycemia occurs and there is no family member to accompany them, which can have serious consequences. Drivers and diabetic patients working at heights should pay special attention to the fact that hypoglycemia may cause accidents. Once there are symptoms of hypoglycemia, the home has a rapid blood glucose meter should immediately determine the finger endings blood sugar, mild hypoglycemia can be relieved by eating sugar water or candy or cookies snacks. Serious cases should quickly call 120 emergency, immediately intravenous injection of 50% glucose water, and sent to the hospital for further resuscitation. It is worth noting that after intravenous injection of 50% glucose water in severe hypoglycemia patients, the patient may turn from coma to wakefulness very quickly, and it is easy to wrongly think that the patient has been safe and sound and not continue to treat and observe, which may lead to the patient falling into coma or even death again. Because the elderly often have renal hypoglycemia, hypoglycemic drugs in the body accumulation is not easy to discharge, although after supplemental glucose hypoglycemia temporarily corrected, but the accumulation of drugs in the body still continue to play a role, some drugs can last for more than 24 hours, when the limited glucose supplementation in a short period of time is consumed, hypoglycemia can occur again, so the correct approach is that the patient becomes conscious! Therefore, the correct practice is that the patient turns awake, should continue to intravenous infusion of 5-10% glucose, and closely monitor blood glucose, at least in the hospital to observe more than 24-48 hours, blood glucose stabilization is safer. Prospective study of diabetes in the United Kingdom showed that from the initial diagnosis of diabetes began to strengthen blood glucose control, can play a significant role in reducing chronic complications of diabetes. And last year announced several large foreign clinical studies suggest that for diabetes disease duration is longer, there have been complications of diabetic patients, intensive glucose control brings limited benefits, while the incidence of hypoglycemia has increased significantly, so diabetic patients must be early diagnosis, early treatment, and to emphasize the individualization of the treatment should be based on the age of the patient, fat and thinness, the duration of the disease, the level of blood glucose, liver and kidney function According to the patient’s age, fatness, thinness, disease duration, blood glucose level, liver and kidney function, etc., the patient should consider comprehensively and formulate a suitable treatment plan, which can not only control the blood glucose well, but also minimize the occurrence of hypoglycemia.