I. High risk factors ：
Gestational period.
① Advanced maternal age ;
②Mother has viral infection;
(3) History of maternal exposure to toxins and radiation;
(4) Fetal ischemia and hypoxia during fetal life: severe maternal anemia, cardiac disorders, psychiatric disorders, gestational toxicity;
⑤ Placental abnormalities, umbilical cord encirclement.
Labor and delivery period.
① Delayed delivery;
②Early abruption of placenta;
③ Placenta praevia;
④Multiple births;
⑤ Abnormal umbilical cord: prolapse, prolapse;
(6) cloudy amniotic fluid;
⑦ Asphyxia;
⑧ Delivery injury.
Neonatal period.
1) Birth weight less than 2.5 kg or more than 4.0 kg;
2. Gestational age less than 34 weeks or more than 43 weeks;
③Gestational age and birth weight do not correspond;
④Respiratory impairment, cardiac arrest;
⑤ Bilirubin encephalopathy, prolonged jaundice;
⑥Intracranial infection;
(7) Intracranial hemorrhage;
⑧ Hypoglycemia;
⑨ Neonatal spasms .
II. Clinical manifestations.
① easy to startle, crying, poor early sucking, difficulty in falling asleep or waking up easily, shaking or twitching of hands and feet after falling asleep
(2) Delayed visual and auditory responses after 3 months of age;
③3 months old still can not lift the head, 4-5 months old head still wobble;
④3 months of age still can’t stand up or take a step;
⑤ 4 months old, thumbs still inward, hands do not open;
⑥After 5 months of age, they do not reach out to grasp objects when they see them;
(vii) Little voluntary movement of the limbs, stiffness of the limbs, difficulty in dressing and undressing, or inability to turn over with flabby muscles;
⑧ premature development: premature rolling over, and sudden reflex rolling over, whole body rolling over like a rolling bucket; stiffness of both lower limbs before sitting down, toe standing position.
Parents should be aware of this knowledge, find the problem, promptly find a neurologist for examination and cooperate with the medical staff’s treatment.