Hepatitis B echogenic thickening and enhancement is generally not serious and is an imaging description during ultrasound. Whether hepatitis B echogenic thickening and enhancement has pathological significance should be judged in the light of the patient’s past medical history, major clinical signs and symptoms, clinical examination and other ancillary tests. If the patient only has thickening and enhancement of the echoes and there are no other medical history or signs, there is no abnormality in the general examination, and it may not have obvious clinical significance. Hepatitis B virus causes chronic hepatitis injury, can be manifested as liver echo thickening and enhancement of the problem, if the obvious thickening suggests that there may be an early stage of liver cirrhosis, the emergence of liver fibrosis manifestations, so it is also necessary to assess the patient’s past medical history and other auxiliary examination. Clinical finding of hepatitis B echo thickening and enhancement of the problem, it is recommended to consult the Department of Infectious Diseases of the regular hospital.