In clinical treatment of high total cholesterol diseases, statins are mainly used, and the representative drugs are lovastatin, atorvastatin, pravastatin, and rasulvastatin, etc., which mainly treat hyperlipidemia with elevated LDL cholesterol. If the effect of normal dose is not obvious, the dose can be increased appropriately according to medical advice. Statins can also stabilize atheromatous plaque, improve vascular endothelial function, delay the degree of atherosclerosis, and have the effects of antithrombotic, hypoglycemic, lowering urinary protein and protecting kidney. However, statins also have certain allergenicity and side effects, which can lead to elevated liver transaminases and aggravate liver damage, which in turn can cause elevated creatine kinase, resulting in muscle lysis, and may also cause rash, insomnia, headache, and nausea. In case of statin side effects, other drugs for hyperlipidemia can be used, such as phenoxyaromatic acid and its derivatives which can lower serum TG and TC and increase LDL-C, especially for patients with combined diabetes. Other lipid-lowering drugs include fibrates, such as fenofibrate, gemfibrozil, benzofibrate, as well as proprietary Chinese medicines, such as blood lipid kang capsule, lipitor capsule and tylipidan capsule, all of which have good lipid-lowering effect.