Nowadays, osteomyelitis is one of the very common health problems, and many of the patients we admit with diabetic foot have a combination of osteomyelitis, which is particularly harmful to the health of the patients. Clinical examination and diagnosis of osteomyelitis: 1. Laboratory tests Blood white blood cell count can be normal, but ESR and C-reactive protein are almost always elevated. 2.X-ray examination X-ray changes appear 3~4 weeks after infection, showing irregular thickening and sclerosis of bone, with residual bone resorption areas or cavities, in which there may be dead bone of different sizes, sometimes no bone marrow cavity can be seen, and some small bone cavities and small dead bone in the sclerotic bone cannot be visualized, so the actual number present is often more than that shown on the photograph. 3.CT examination If the X-ray performance is not clear, CT examination is feasible to determine the lesioned bone and show the formation of paravertebral abscess. 4.Biopsy For fractures and tumors, puncture biopsy and surgical biopsy of the intervertebral disc space or infected bone can be performed, and bacterial culture is feasible. 5.Iodine oil imaging In order to clarify the relationship between dead bone or bone cavity and sinus tract, iodine oil or 12.5% sodium iodide solution can be used for sinus tract imaging. Western medicine treatment: symptomatic treatment is the main treatment, according to the culture and drug allergy to choose sensitive antibiotics to control infection; thorough removal of dead bone and surrounding inflammatory tissue with poor blood flow at the lesion, and removal of inflammatory tissue in the bone marrow cavity. Traditional Chinese medicine treatment: Guided by the theory of simmering pus and generating muscle in Chinese medicine, combined with the actual development of the patient’s condition, we apply special muscle-generating cream and muscle-generating powder to the wound surface to remove decay and generate muscle, based on clinical evidence of “poisonous heat”, “blood stasis”, “pus and decay”, “weakness of qi and blood” and other conditions. The combination of Chinese and Western medicine, taking advantage of the strengths and weaknesses, combining disease identification and evidence identification, and combining local and overall, can achieve good results in the treatment of osteomyelitis.