What should I do if my disease progresses after sotan treatment for kidney cancer?

For patients with metastatic kidney cancer after treatment failure with sorafenib or sunitinib, everolimus was approved by the US FDA in 2009. Everolimus is an orally administered mTOR inhibitor. The relevant evidence was derived from data from a phase III clinical trial for the treatment of metastatic kidney cancer that had failed previous targeted therapy, with a median progression-free progression interval of 4.9 months for everolimus compared to placebo or blanket therapy. Axitinib is an emerging multi-targeted receptor complex kinase inhibitor that has been approved by the FDA for second-line treatment of advanced kidney cancer in early 2012. A phase III clinical trial comparing axitinib with sorafenib for metastatic kidney cancer that has failed previous targeted drug therapy found that axitinib was superior to sorafenib. Of these drugs, axitinib and pazotinib have not yet been available in China, but everolimus was launched in China in 2014 for patients who had failed prior treatment with sorafenib or sunitinib. Aggressive treatment of metastatic lesions may also help relieve painful symptoms of kidney cancer patients and may prolong survival. The Department of Integrative Medicine and Medical Oncology of China-Japan Friendship Hospital has carried out minimally invasive treatment of metastatic lesions of kidney cancer and achieved good clinical efficacy. The effective cases of lung metastasis of kidney cancer treated with TCM in our department are reported as follows: a male, 64 years old, was diagnosed with renal cell carcinoma in May 2010, and his right kidney was surgically removed, pathology report: renal clear cell carcinoma, mass 8cm, reaching fascia. After surgery, no adjuvant therapy, in 2012, chest CT showed multiple small nodules in both lungs, metastases are not excluded, size 0.7cm. Chinese medicine treatment to clear the lungs and kidneys, soften the hardness and dispersion of golden buckwheat 15g, fishy grass 10g, loquat leaf 10g, wood butterfly 10g, Chinese wolfberry 20g, chasteberry 15g, dogwood 10g, zhebei 15g, BaiBu 10g, orris 15g, QianHu 10g. The medicine was taken with water for one dose per day. After 3 months of medication, the metastases in the lung were reduced on review.