Mercury poisoning-related nephrotic syndrome is often treated as “primary nephrotic syndrome” because no secondary cause can be detected in routine tests. 1. How did mercury poisoning occur? In the past, mercury poisoning was often obtained in industrial production, but now the situation is completely different; to give some examples, illegal traders, in order to make a profit, in the cordyceps mixed with mercury, lead and other heavy metals, the characteristics of such patients are particularly serious disease, typical symptoms, blood and urine mercury content exceeds the standard is extremely significant, and these patients are often some of the upper social class, at least is also mixed with the better class; Chinese medicine Zhu Sha The content of mercury is very high, some “ancestral recipes”, herbal fumigation therapy, there may be mercury poisoning; cosmetics, hair dyes, especially the former in the content of mercury may be another jaw-dropping! Since mercury can inhibit pigmentation and greatly enhance the whitening effect, it has been adulterated in large quantities by unscrupulous traders. The number of kidney syndrome caused by cosmetics is now really increasing, and it is simply surprising to you, and the concealment is quite good and not easy to be found. 2, why cosmetic-related mercury poisoning is now more and more? First of all, the soil is fertile: urbanization, rich, stink a little, a variety of whitening training courses, whitening treatment, three days rapid whitening, and so on, prevalent. There are more and more small stores, and a lot of online shopping: not to say that the foreigners are pandering to foreigners, Chinese counterfeit goods are great! Chinese counterfeiting technology is very clever, many fake and real, and even some stores, selling the real product is not the original import, but the domestic production, although authorized by the foreign, but to the hands of the Chinese, often may be out of shape. (I’m really not a fan of foreigners, you guys shoot brick when light). In addition, there is another point, you know what? On the issue of excessive mercury in cosmetics, there is no unified quality control standards in China, so buying cosmetics is often a matter of luck, good luck, all right; bad luck, suffer. We call on the state to develop such standards as soon as possible, but also caution all beauty lovers to buy authentic products. Or simply do not stink of beauty. 3, the clinical manifestations of mercury poisoning? Acute mercury poisoning is often dominated by neurological manifestations, within the first few days – months, the patient will become anxious, irritable, insomnia, muscle aches, followed by swelling of the eyelids and both lower limbs, and gradually proteinuria and nephropathy in severe cases. The textbook says there are also written skin manifestations, digestive tract, hematologic manifestations or something, but I feel that these manifestations are not obvious. In general, the neurological and urinary systems are the most typical, with the former predominating in the early stages and the latter in the later stages. Many people are treated by neurology in the early stage, and finally after half a day of investigation and treatment, they are given a label of “hysteria” by doctors. A patient from Ningbo said, “I can’t sleep all night, but I’m definitely not neurotic, my brain is very clear”! From Ningbo local hospitals to Hangzhou, Shanghai, and finally to a top hospital in Beijing, no one mentioned the possibility of mercury poisoning in the differential diagnosis! Then she went online, read a book, suggested the doctor to prescribe a toxicology test, and finally, saved herself! This is not uncommon, but of course the doctor can’t be blamed for this misdiagnosis, after all, this kind of cosmetic-related mercury poisoning has only appeared in the last 10 years or so, and it’s really not well understood. 4. What happens when you don’t treat mercury poisoning? It is often fine if you don’t treat it. The body has a good ability to excrete mercury itself, mainly in the urine. Unless the amount is particularly large, generally speaking, 50ng/ml of blood mercury can be excreted completely by itself in two months, but during this process, the patient’s renal syndrome symptoms may be very heavy, and some even need ultrafiltration to pull water, renal function progress, and regular supplementation of colloid, and if hormones are used rashly, the patient’s resistance will be even lower, and even dangerous. Most of the patients who are treated as “hysteria” or “primary renal syndrome” are generally fine, after all, they are hospitalized, basically they won’t look good anymore, and they won’t go to various whitening classes, so the mercury exposure will naturally stop, and the mercury will slowly be The mercury exposure will naturally stop and the mercury will slowly be discharged. 5.How to cure mercury poisoning? It is very simple, and there is a lot of information in the books, and it is also very clear. Mercury-based drugs are cheap and can be used by poor farmers. The effect is good, the key is to want to get. 6.What is the prognosis of mercury poisoning-related nephropathy? At present, there are about 30 cases of mercury poisoning nephropathy with renal puncture results, and the most common pathological types are MN, MCD, FSGS, especially MN, which accounts for almost 80%. 28 cases have disappeared within two months after mercury expulsion; the other two cases will slowly reach 1.0g after half a year, and are still being followed up in outpatient clinics. (The data is a bit rough, but it is not too far off); there is another case, because the physical examination found that both kidneys are atrophied, because the urine volume has always been there, the swelling is not too obvious, and has not been seen. When she came to see her very thin woman, double kidney atrophy, well, creatinine on more than 100 points, occupational habits, asked the mercury exposure history, replied that the first two years adhere to whitening, has been bad sleep, sometimes swelling, the two years do not work, the husband raised, the last six months white indeed also beautiful, plus the body is always tired, so stop whitening. Decisively check the blood urine toxicity test, are over the standard, but not much over the 2.8ng/ml, estimated to be their own discharge. Tragic. But overall, the prognosis for mercury poisoning is good.