Creatinine should not be used as the only indication for dialysis. The choice to do dialysis should be fully evaluated and based on the patient’s ancillary tests and clinical vital signs, whether dialysis is performed. Most commonly, dialysis is recommended for patients with chronic renal failure with creatinine over 707 μmol/L. However, dialysis is required even if the creatinine value is not high if the following conditions occur: 1. A relatively high cardiac load, uncontrollable hypertension, pulmonary edema, uncontrollable hyperkalemia, hyperphosphatemia, hypercalcemia, hypocalcemia all require dialysis; 2. Patients with uremic encephalopathy or neurological symptoms require dialysis even if the creatinine does not reach the value; 3. There are also some patients with abnormal cardiac function and gastrointestinal symptoms are difficult to correct, and dialysis can also be performed in the case of not high creatinine; 4. Some patients with drug intoxication and poor blood perfusion can be considered for dialysis. Therefore, the creatinine value should not be used as a criterion to determine whether dialysis should be performed.