The results of a large number of clinical studies show that comprehensive treatment is the fundamental guarantee to improve the efficacy, which requires close cooperation among specialists in the disciplines of surgical oncology, medical oncology, radiotherapy, radiology and pathology, and it is best to reach a consensus before any treatment is started to determine the best long-term treatment plan based on adequate staging. 1.Tumor can be resected and in good physical condition (more than half of the patients): Those with preoperative clinical staging of T1 or T1 or less are treated by direct surgery; T2 or T2 or above can be treated by chemotherapy or chemoradiotherapy followed by surgery in addition to direct surgery. After surgery, the next treatment is decided according to pathology: T1N0: no further treatment is needed, follow-up; T2N0: no further treatment, but also postoperative chemotherapy (fluorouracil-based) if the tumor is hypodifferentiated, lymphovascular infiltration, nerve infiltration, or less than 50 years old; T3, T4, or any T when there is lymph node metastasis, or residual tumor after surgery (microscopic or naked eye findings). Both give chemoradiotherapy → chemotherapy (fluorouracil-based sensitizing radiotherapy and follow-up chemotherapy), or combination chemotherapy (those who had FOLFOX preoperatively are still treated with 8 cycles of chemotherapy with this regimen after surgery). 2. If the tumor can no longer be removed, or if the patient is in poor physical condition and cannot be operated: chemoradiotherapy: radiotherapy + fluorouracil-based sensitizing chemotherapy chemotherapy, palliative treatment Radiotherapy for gastric cancer is more commonly done in the United States, and radiotherapy for gastric cancer has high requirements for simulated positioning, treatment planning and target area setting. The radiotherapy dose is 45-50.4 Gy (1.8Gy per day). 3. Once metastasis is detected, palliative treatment should be given either at the beginning or in the course of treatment. Chemotherapy is the most effective palliative treatment and is suitable for those who can get out of bed for more than half a day during the day. Other treatments: nutritional support (enteral nutrition and nutritional guidance), relief of obstruction (stenting, laser, radiotherapy or surgery), pain control (radiotherapy and/or drugs) and hemostasis (radiotherapy, surgery or endoscopic treatment).