Gallstones is a common disease, medical research found that the onset of gallstones and physical, diet, disease and many other factors, so who are vulnerable to gallstones? 1, women, women account for 70% of gallstones patients, and the more pregnancies, the higher the incidence. Because of the high level of estrogen in women’s body, it will affect the formation of bilirubin glucuronide in the liver and increase the unconjugated bilirubin. 2, cirrhotic patients, the incidence of gallstones in cirrhotic patients is significantly higher than normal people, which is related to the reduced inactivation of estrogen in the body of cirrhotic patients, higher estrogen levels, as well as chronic hemolysis, low gallbladder contraction, poor gallbladder emptying, biliary varices, elevated bilirubin in the blood and other factors. 3, obese people, weight more than 15% of the normal standard, the incidence of gallstones than normal people 5 times higher, 20 to 30 years old obese women gallstones incidence than the normal weight of the same age 6 times higher, more than 60 years old obese women 40% have gallbladder disease and gallstones. 4, diet meat, sweet or do not eat breakfast diet meat like sweet, their fat and cholesterol intake, easy to form cholesterol stones; too much sweet food and promote insulin secretion, will accelerate cholesterol deposition; often do not eat breakfast will reduce the content of bile acid, bile concentration, conducive to stone formation. 5, too much sun exposure, such as farmers and people who like sunbathing, are prone to gallstones. 6, too little exercise, too little exercise will affect the function of the digestive system, the bile is easy to stagnant stagnation, difficult to excrete. 7, the body has roundworms, unclean diet infected with roundworm disease, roundworms reflux to the biliary tract to lay eggs or die, it will become the core of stones, generating stones.