The clinical symptoms of severe schizophrenia are complex, involving perception, thinking, emotion, volitional behavior and cognitive function. For example, patients may have the following symptoms: 1. perceptual disorders: mainly hallucinations, including hallucinations of hearing, vision and smell, etc. 2. thought disorders: there are many kinds of delusions, such as delusions of victimization, relationship delusions, jealousy delusions, exaggerated delusions, non-pedigree delusions, etc. 3. affective disorders: emotional indifference and incoordination of emotional responses are common, in addition to abnormal excitement, irritability, depression and anxiety, etc. 4. will and Behavioral disorders: Most patients are isolated, disinterested in work, learning and the future, and have no plans for the future. 5. Cognitive dysfunction: There are significant deficits in attention, working memory, short-term memory, learning and executive functioning. 6. Self-injury or violent behavior: In severe cases, there is self-injury or violent injury. The above abnormal manifestations make schizophrenia patients a heavy burden on society and families. Usually, long-term medication is the main treatment for patients with severe schizophrenia, but some patients still have the following conditions: 1. medication cannot effectively control certain psychiatric symptoms 2. patients refuse to take medication or have serious side effects after taking medication 3. violence is difficult to control and is a danger to society and families. Currently, surgery for refractory schizophrenia has become an important treatment tool. This method is a stereotactic minimally invasive treatment technique, which has better control of refractory psychiatric symptoms and makes it easier for family members to manage the patient. However, patients’ families still have the following misconceptions about the procedure. Functional neurology experts have answered these questions. 1.Surgery leads to disability: The target of surgical treatment is chosen in the nucleus accumbens in the emotional circuit, not in the area of the nerves that govern movement, so the treatment itself will not cause disability 2.Surgery leads to dumbness: The surgical area is not in the frontal lobe and other areas that control intelligence, so it will not lead to dumbness and other conditions 3.Surgical trauma: The surgical incision is only 3 cm, the skull is perforated 3~5 mm, the electrode into the brain is 2 mm The theoretical positioning deviation of the nucleus accumbens is no more than 1 mm, and the diameter of the nucleus accumbens is about 10~15 mm. The stereotactic neuromodulation technology ensures that the electrodes can accurately enter the nucleus accumbens for treatment, so the surgical trauma is very mild, and you can walk on the ground and eat normally on the second day after surgery. In conclusion, surgery is a treatment option available for severe schizophrenia. However, whether the patient is suitable for surgery and whether the physical condition allows him/her to receive this treatment method, all these need to be examined in detail and carefully evaluated by the functional neurology expert team, and the family needs to make a careful decision.