Transaminases cannot be lowered, may be physiological high, hepatitis B, steatohepatitis, alcoholic hepatitis and other reasons, according to its cause to give general treatment, drug treatment. 1. Physiological high: high transaminases caused by strenuous exercise or overwork can be gradually reduced through rest; high transaminases in pregnant women can not be reduced, and can gradually return to normal after delivery, so no special treatment is needed for the time being. 2. Hepatitis B: high transaminases caused by viral hepatitis B can be given antiviral treatment, such as entecavir, lamivudine, etc. to promote the decline of transaminases, and it is recommended to use five ester capsules to protect the liver. 3. Non-alcoholic steatohepatitis: adjust dietary habits, light diet, and strengthen exercise, weight control, reduce the fat content of the liver, and apply liver protection tablets to promote the gradual return of aminotransferases to normal. 4. Alcoholic hepatitis: Strictly abstain from alcohol, give reduced glutathione, five ester capsule, diammonium glycyrrhizinate capsule, etc. to protect liver and reduce enzyme treatment. If the transaminase does not come down, it is recommended to consult a doctor in time to find out the cause of the disease and standardize the treatment. Drugs should be taken in accordance with medical advice.