Chronic eczema want to treat the root cause, can be through general treatment, topical drug treatment, oral drug treatment and other methods of comprehensive treatment, in order to be able to fundamentally cut off the recurrence of chronic eczema. 1. General treatment: It is necessary to actively search for the cause of the disease and remove the possible causes or allergens; in addition, it is necessary to pay attention to reducing the external stimuli, such as violent scratching, excessive wiping, hot water scalding, etc., and avoiding the intake of allergy-prone foods, such as fish, shrimp, alcohol and so on. 2. External drug treatment: (1) Glucocorticoid: it is one of the main drugs for chronic eczema. For mild chronic eczema, it is generally recommended to use weak glucocorticoid drugs such as dexamethasone cream and hydrocortisone ointment for topical treatment; for severe hypertrophic eczema, it can be treated with strong glucocorticoid drugs such as halometasone ointment. (2) Immunomodulators: such as the commonly used tacrolimus cream, pimecrolimus cream, etc., which can regulate the skin immunity, enhance the resistance of the skin and promote the recovery of the disease. 3. Oral drug therapy: such as commonly used antihistamines, can play the role of anti-inflammatory, anti-allergic and anti-itching, so for patients with severe itching, oral loratadine, cetirizine and other treatment. As each patient’s condition is different, so the specific drugs need to be taken under the guidance of a professional doctor, to avoid blind use of medication affects the health of the body.