In clinical work, it is increasingly found that about 80-90% of primary liver cancer patients have hepatitis, and most of these liver cancer patients have a history of hepatitis for more than 10 years, and the age is getting younger. Hepatitis and liver cancer are closely related, and the areas with high incidence of liver cancer are also the areas with high incidence of hepatitis. Hepatitis B, C, and D are the main types of hepatitis associated with liver cancer, especially the first two, while hepatitis A and E are not associated with liver cancer. Hepatitis virus mainly activates oncogenes by interfering with DNA replication in normal cells, causing liver cell carcinogenesis; hepatocytes affected by hepatitis virus that undergo necrosis are susceptible to various carcinogenic factors during proliferation, which is another reason why hepatitis virus causes liver cancer. Long-term chronic inflammation will cause the proliferation of liver fibrous tissue, and the massive proliferation of fibrous tissue makes the liver harden, which is what we call cirrhosis. When cirrhosis continues to develop until liver function cannot be effectively compensated, serious complications such as liver ascites and upper gastrointestinal bleeding can occur. The following symptoms may appear in the early stage of liver cancer: 1. pain in liver area, mostly persistent dull pain, swelling pain or stabbing pain. 2. 2. Systemic and gastrointestinal symptoms, such as weakness, emaciation, loss of appetite, abdominal distension, some of which may be accompanied by nausea, vomiting, diarrhea, jaundice, ascites, swelling of lower limbs and cachexia in advanced stage. 3, liver enlargement, manifested as an epigastric mass, is the main sign common in patients in the middle and late stages, a few patients occasionally felt and become the first symptoms. Active prevention and control of hepatitis is an effective means to prevent and control cirrhosis and liver cancer. Starting from infants to uninfected adults, preventive vaccination against hepatitis B, paying attention to dietary hygiene and avoiding bad living habits can reduce the chances of hepatitis; hepatitis should be treated actively to prevent it from evolving into chronic hepatitis; chronic hepatitis should be treated reasonably to avoid the application of drugs that damage the liver. For people over 35 years old with hepatitis B surface antigen (+); those who have chronic hepatitis and cirrhosis for more than 5 years; those who have a history of liver cancer in three generations of their immediate family members should have AFP and liver ultrasound examination once every six months. To achieve early detection and treatment.