The possibility of sudden death during recovery from craniotomy may be due to the presence of intracranial lesions or extracranial complications. 1. Intracranial lesions: when the patient has intracranial lesions leading to intracranial infection or acute massive cerebral infarction, it can lead to an increase in intracranial pressure, causing the patient to die suddenly. 2. Extracranial complications: during the recovery period of craniotomy, if serious lung infection or lower extremity venous thrombosis leads to pulmonary embolism, it can also lead to sudden death. It can be combined with relevant cranial CT, blood routine, coagulation function examination, D-dimer examination, lower extremity venous ultrasound and other examinations to make timely judgment on the patient’s condition in order to avoid the occurrence of sudden death. Patients recovering from craniotomy have the possibility of sudden death. It is recommended to closely observe the patient’s condition after surgery and inform the doctor in time if there is any abnormality to avoid serious consequences.