The different thickness of the legs may be caused by the following reasons: 1, may be due to poor posture, many patients are used to sitting and standing on the legs, over time, it may cause the legs placed on it due to insufficient blood supply, resulting in muscle malnutrition, which will lead to double lower limb thickness. 2, is due to lower limb vascular disease, for example, if there is an arterial embolism on one side of the lower limb, it will cause insufficient nutrient supply to this side of the lower limb. For example, if there is an arterial embolism on one side of the lower limb, it will cause insufficient nutrient supply to this side of the lower limb, which in turn will make it thinner.