Different thickness of the calf can be seen in the following cases: First, muscle atrophy of the lower limbs, especially with a history of lumbar disc herniation, local nerve root compression, and without timely and effective treatment, muscle atrophy can occur. Patients will have lower back pain, lower limb numbness as well as swelling and pain in the usual performance, should be appropriate functional exercise, physiotherapy. Second, some patients are secondary to the sequelae of cerebrovascular disease, will appear inflexible limb activities, will also appear muscle atrophy, manifested as lower limb swelling or lower limb circumference is not the same. Third, some patients are caused by venous thrombosis, which manifests as swelling, congestion, edema, increased skin temperature, and even obvious exudation of the limbs.