Swelling of the right leg, which is thicker than the left leg, is mainly caused by the following two diseases: the most frequent disease is lymphangitis of the lower extremity, which is usually caused by bacterial infection due to skin cracking, and the infecting bacteria is usually Streptococcus haemolyticus, and its clinical manifestations are mainly redness, swelling and heat, which can be accompanied by swelling. The main treatment is to use antibiotics that are sensitive to Streptococcus haemolyticus, mainly penicillin or a generation of cephalosporins. The second common condition is swelling and even painful discomfort in the lower limbs due to prolonged bed rest in elderly patients, which causes slow blood flow secondary to the formation of deep vein thrombosis in the lower limbs. The diagnosis of lower limb deep vein thrombosis usually requires further ultrasound examination of lower limb deep vein to clarify the diagnosis, and after the diagnosis of lower limb deep vein thrombosis is clear, it usually requires placement of a filter and thrombolytic therapy.