Running knee pain may be due to meniscus injury, goosefoot bursitis, chondromalacia patella, arthritis and so on. 1. Meniscus injury: improper exertion or over exertion during running may cause meniscus tear, causing irritation and usually knee pain. 2. Goosefoot bursitis: It is usually the symptoms of swelling, heat and pain, and activity limitation in the lower medial part of the knee joint, which will lead to pain and discomfort in the knee during running and affect normal running. 3. Chondromalacia patella: mostly occurs in young athletes, the main symptom is pain behind the patella of the knee joint, the degree of severity varies, which will make the patient’s knee experience severe pain during running. 4. Arthritis: Knee arthritis will lead to localized swelling and pain in the joints, and in severe cases, it will also be accompanied by activity limitation, which will cause joint deformity in severe cases. Patients in the discomfort symptoms, to avoid blindly determine the cause of the disease, the need to improve the relevant examination, under the guidance of a professional physician to clarify the cause, and timely treatment.