Enlarged heart usually refers to myocardial hypertrophy, dilated heart disease, pericardial effusion, the treatment should be based on the specific cause of the disease, follow the doctor’s instructions to choose chlorosartan, nifedipine and other drug therapy, if necessary, surgical treatment and other programs. 1. Myocardial hypertrophy: (1) If the cardiac hypertrophy is caused by hypertension, it can be treated by controlling blood pressure and choosing angiotensin-converting enzyme inhibitors, calcium antagonists, angiotensin di-receptor antagonists, and β-blockers, such as chlorthadiazepoxide, nifedipine, captopril, and other drugs. (2) If myocardial hypertrophy is caused by aortic valve stenosis, the stenosis of the valve should be relieved by interventional therapy, balloon dilatation or surgical valve replacement. (3) If myocardial ischemia, myocardial infarction caused by myocardial fibrosis, myocardial hypertrophy, it is necessary to carry out thrombolytic or interventional therapy in time to relieve myocardial ischemia. 2. Dilated cardiomyopathy: dilated cardiomyopathy can be caused by cardiac infarction, pulmonary hypertension, etc., and a few of them are primary with unknown etiology. For treatment, those with heart failure should be treated with diuretics, cardiotonic drugs and vasodilators; patients with history of embolism should be treated with anticoagulation; those with arrhythmia should be treated with antiarrhythmic drugs or electrical modalities. 3. Pericardial effusion: Pericardial effusion can be caused by infection, trauma, tumor, heart failure, renal failure, etc. When pericardial effusion is too much and symptoms of dyspnea appear, surgical drainage can be performed to relieve the symptoms quickly, but pericardial effusion focuses on the treatment of its primary disease. Myocardial hypertrophy, dilated heart disease is an irreversible course of the disease, can not be ignored, early detection, early treatment is important; pericardial effusion treatment focuses on identifying the cause of the disease, the treatment of the cause in order to have the best efficacy.