The determination of the benign or malignant nature of a breast nodule is usually determined by a physical examination by a physician, imaging of the breast and pathologic examination of the nodule by puncture or excision. Physical examination by a doctor is mainly done by observing whether there is any change in the appearance of the breast or by touching the nodule to make a preliminary judgment based on the characteristics of the nodule. Generally, benign nodules are softer in texture, smoother on the surface, have clearer boundaries with normal glands, and have a more regular shape and better mobility. Breast imaging tests include breast ultrasound, mammography, and breast magnetic resonance imaging (MRI). Doctors in the breast imaging department determine the benign or malignant nature of a nodule based on the morphology of the nodule, its shape, its boundaries, and the blood flow signal of the nodule. When the doctor is unable to determine the benign or malignant nature of the nodule from physical examination and imaging, the most accurate way to determine the benign or malignant nature of the nodule is to examine the nodule by puncture or excisional pathology.