Nodules in the shoulder and neck are usually due to muscle strain in the cervical spine or shoulder, and over time, localized aseptic inflammation occurs, and the formation of localized inflammatory nodules occurs. It can also be caused by cervical spondylosis, where degenerative changes in the cervical spine compress the nerve roots, leading to pulling pain in the nerves, and chronic muscle tension, which over time can also lead to localized aseptic inflammation, resulting in the formation of nodules. Inflammatory nodules of the muscle, when pressed, will appear very obvious pain, can be localized through the massage, massage and other physical therapy or topical ointment, the symptoms can be slowly relieved. However, it is important to note that if the nodules are localized and there is no pain, they may be caused by other reasons. The most common are subcutaneous swellings such as sebaceous cysts, fibromas, and lipomas. It is basically possible to identify them by localized ultrasound.