What are the symptoms and manifestations of advanced kidney cancer?

  Renal tumors are more common among urological tumors, second only to bladder tumors. The vast majority of primary renal tumors are malignant, including renal cell carcinoma, nephroblastoma (Wilms tumor), and renal pelvis cancer. Due to longer average life expectancy and improved imaging techniques, the incidence of kidney cancer has tended to increase, and the number of kidney cancers detected incidentally during physical examination without clinical symptoms is gradually increasing. The clinical occurrence rate of the classic “triad of kidney cancer”, including hematuria, lumbar pain and abdominal mass, is less than 15%, and these patients are often diagnosed at an advanced stage. The detection rate of asymptomatic kidney cancer is increasing year by year (about 50%), and 10%-40% of patients have paraneoplastic syndrome, which is characterized by hypertension, anemia, weight loss, cachexia, fever, erythrocytosis, abnormal liver function, hypercalcemia, hyperglycemia, increased sedimentation, neuromuscular lesions, amyloidosis, overflow, abnormal coagulation mechanism, etc. 30% of patients have metastatic kidney cancer, which can They can be seen for symptoms such as bone pain, fracture, cough and hemoptysis due to tumor metastasis. Among patients with metastatic kidney cancer, the incidence of metastatic organs is 48.4% for lung metastasis, 23.2% for bone metastasis, 12.9% for liver metastasis, 5.2% for adrenal metastasis, 1.9% for skin metastasis, 1.3% for brain metastasis, and 7.10% for other sites. Among them, 11.9% of patients had multi-organ metastasis.  The efficacy of late stage kidney cancer is not good, and the efficacy of kidney cancer detected in early stage is better. It is recommended that we should pay attention to our health and attend regular medical checkups, especially after the age of 45, we should develop the habit of going to the hospital for comprehensive health checkups regularly (generally recommended once a year).