Sepsis is a systemic infection syndrome in which pathogenic microorganisms invade the blood circulation and grow and multiply, producing large amounts of toxins and metabolites that cause severe toxemia symptoms. Sepsis is a curable disease and generally does not affect life expectancy. However, there are several special cases that are not easily cured and may be life-threatening at any time in severe cases. For example, in elderly people or infants with poor immunity, sepsis has a rapid onset and progression, lacks typical symptoms, and has a high mortality rate; sepsis is often complicated by large deep burns, and the clinical manifestations are usually severe; patients in the intensive care unit have severe underlying diseases, and their sepsis occurring in the hospital often causes multi-organ failure, which is poorly treated and has a poor prognosis. Most cases of sepsis in general can be cured with aggressive treatment. Treatment of sepsis first requires identification of the primary lesion and timely cutting off the pathway of infection. Then, according to the results of bacterial culture and drug sensitivity test, choose the appropriate antibiotics, timely, combined, adequate intravenous administration of drugs for about 2 weeks, or after the body temperature is normal, the symptoms disappear and then continue to use drugs for 5-7 days. Patients with shock should also receive timely anti-shock treatment, correct water-electrolyte disorders, and maintain acid-base balance to maintain the stability of the internal environment. Patients with sepsis need a lot of nutritional support during treatment, and can eat more high-protein, high-calorie foods. Also pay attention to keep the skin clean and dry, avoid scratching the skin, good hand hygiene, etc.