The cause of pain from kidney stones is smooth muscle spasm, which can be treated with symptomatic pain relief, stone removal treatment or stone extraction treatment. 1, the simplest and most common method is to drink more water, so that the daily urine volume is maintained at 2000-3000ml, with the release of spasm drugs, which is conducive to the discharge of small stones. 2. Symptomatic pain relief treatment. Usually the first use of non-steroidal anti-inflammatory drugs, such as the use of indomethacin pessary anal plug. If the pain is still not relieved, you need to choose weak opioid analgesics such as tramadol or strong opioid analgesics such as pethidine. Be sure to use antispasmodic drugs such as 654-2 when using opioid analgesics. 3. Lithotripsy treatment. For smooth stones less than 6 mm in diameter, if there is no obstruction in the urinary tract below the stone and the stone does not cause complete obstruction, stone removal flush can be taken with more water and proper exercise to help the stone discharge. α-blockers and calcium ion blockers also have the effect of soothing the smooth machine and promoting the discharge of kidney stones to the ureter, to the bladder, and to the outside of the body. If these treatments do not work, extracorporeal shock wave lithotripsy, ureteroscopy or percutaneous nephrolithotomy can be considered. In short, only when the stones are expelled from the body can the kidney stone pain be cured.