People with ankylosing spondylitis have pain when lying down. Ankylosing spondylitis due to the involvement of the central axis bones, large joints of the limbs and the spine, usually appear symptoms such as morning stiffness, joint pain, low back pain, etc. Ankylosing spondylitis pain when lying down may be due to the spine and sacroiliac joints ankylosis, deformity and joints are extruded when lying down. Ankylosing spondylitis patients lying down will hurt this symptom can be symptomatic treatment of drugs, commonly used drugs such as non-steroidal anti-inflammatory drugs such as meloxicam, etc., can be effective in relieving the pain symptoms of patients. But also need to comply with the doctor’s instructions to take oral sulfasalazine pyridine and other drugs to treat ankylosing spondylitis this disease. In daily life, pay attention to avoid the cold, pay attention to joint warmth, suitable for sleeping on a hard board bed and choose a lower height of the pillow or do not use a pillow. Ankylosing spondylitis patients lying down will hurt this symptom can be to the regular hospital rheumatology and immunology department for related consultations, and under the guidance of the doctor for standardized diagnosis and treatment, regular follow-up.