Clinically, if estradiol decreases, it will cause some corresponding clinical symptoms, such as thin endometrium, reduced menstrual flow, and decreased libido, so treatment should be given clinically. For example, diet can be adjusted by drinking fresh soy milk, royal jelly, black beans, peanut butter, onions, etc., which can supplement estradiol. In addition, it is necessary to give treatment with medication, for example, starting to take oral supplements on the 5th day of menstruation, taking 1 tablet once a day for 21 days, and adding progesterone capsules orally for the last 10 days, taking 2 capsules once a day, after stopping the medication, waiting for the onset of menstruation. After stopping the medication, wait for the onset of menstruation. Repeat the treatment from the 5th day after the onset of menstruation for 3 consecutive menstrual cycles.