Most men who undergo treatment for enlarged nipples are men because their nipples are more exposed to the public. Enlarged or overgrown or even drooping nipples in men are called feminized nipples in men. They do not always occur at the same time as gynecomastia, can be bilateral or unilateral, and the cause is unknown and may be related to hormonal abnormalities. An enlarged nipple is a small but particularly striking deformity that often causes psychological stress to the patient. Women who are breastfeeding often have enlarged or overgrown nipples that affect their aesthetics, and more and more women are coming to the hospital for nipple reduction surgery. Through surgery can correct the nipple is too large, can choose the central part of the nipple excision, or nipple side excision; can also choose the top part of the nipple wedge-shaped excision. Nipple reduction surgery is simple and safe, and the post-operative results are excellent. The patient will be psychologically improved after the surgery, which will benefit the patient physically and mentally. The surgical methods include Sperli’s method, Yasuo Muto’s method, and the hemisided nipple excision method.