Depending on the amount of tissue obtained, the main methods of biopsy of breast lumps are needle aspiration, or hollow needle (thick needle) aspiration, and direct lump excision for biopsy. In general, we use a fine needle to aspirate some cells from the mass by negative pressure to do cytological testing. The hollow needle has a special biopsy needle that can take out a thin strip of tissue from the mass for laboratory testing; the last method is direct mass excision biopsy. There are definitely differences between these methods. It is easier and less invasive to use a fine needle with a syringe, but it can only aspirate a few cells, so the amount of tissue in these cells is very small and sometimes it is difficult to confirm the diagnosis. Nowadays, fine needle aspiration is no longer used as a method of diagnosis, and is only used for biopsies of lymph nodes. Coarse needle aspiration, also known as hollow needle aspiration, is one of the most commonly used methods of mass biopsy, which allows for the extraction of a relatively large amount of tissue or a relatively large amount of tissue strips, which can clearly diagnose the nature of a breast mass. If we want to get rid of breast lumps, we must first identify what kind of nature the breast lump is, and how the breast lump was found, whether it was palpated and felt by ourselves, or palpated and felt by the doctor, or found by ultrasound, or mammogram or MRI. For breast lumps of different nature, they are all treated differently. If there is a clear finding of an occupying lesion in the breast on ancillary tests, it may only be removed surgically.