Does labor analgesia have any effect on the mother’s health in the long term after delivery? Labor analgesia may reduce the incidence of maternal postpartum depression. The Department of Anesthesiology at Peking University First Hospital recently collected data on the basic prenatal conditions, delivery time, and maternal and infant status of 214 full-term primiparous mothers at the hospital, and assessed depression at 42 days after delivery. Among them, 107 women voluntarily received epidural labor analgesia and 107 women had no analgesia. The results showed that the prevalence of depression at 42 days postpartum was 14% and 29% in the women with and without labor analgesia, respectively. Professor Wang Dongxin, director of the department, pointed out that postpartum depression is a common postpartum psychiatric disorder, which mainly manifests as postpartum depression, excessive self-blame and anxiety, and suicide attempts. For most first-time mothers, the pain of childbirth is similar to the pain caused by cutting off a finger, and the trauma caused by severe pain may lead to an increased chance of postpartum depression. Domestic literature records that the incidence of postpartum depression ranges from 10.1% to 40.8%, and the diagnosis is made 1 month to 2 months after delivery.