Hepatitis B protective antibody will disappear after you have hepatitis B protective antibody. If you need to keep hepatitis B antibody effectively, you need to get hepatitis B vaccination regularly. Hepatitis B antibody is more, the most common are surface antibody, E antibody and core antibody, among them, hepatitis B surface antibody will gradually decline or disappear over time, if you need to ensure that the hepatitis B antibody exists continuously and effectively, you need to review regularly, and when the antibody titer decreases, you need to strengthen the hepatitis B vaccine under the guidance of the doctor. At the same time, most of the hepatitis B antibody can be maintained for 3~5 years, but there are individual differences, if you find that the body’s hepatitis B antibody is too low or disappeared, you should be timely re-vaccination of hepatitis B vaccine. It is recommended to regularly monitor the hepatitis B antibody in one’s body and reasonably vaccinate according to one’s own situation to ensure the continuous and effective existence of the antibody.