Hard lumps in the palm of the hand after carpal tunnel syndrome surgery are considered to be caused by local soft tissue adhesion, scar formation, suture reaction and other factors. 1. Soft tissue adhesion: Carpal tunnel syndrome surgery will cut the transverse carpal ligament and the rest of the tissues, which may damage the local small blood vessels, resulting in postoperative local bleeding and hematoma formation. It may cause local soft tissue adhesion and hard lumps. Postoperative wound infection can also lead to soft tissue adhesions. 2. Scar formation: the surgical incision of carpal tunnel syndrome usually extends more to the palm side, due to the individual’s physical condition, local scar formation can occur, and hard lumps appear in the palm of the hand. 3. Suture reaction: postoperative suture reaction is a kind of rejection reaction of human tissues to the stimulation of foreign materials, which can cause local suture wrapping mechanization and hard lumps can be touched in the palm area. When patients with carpal tunnel syndrome find hard lumps in their palms after surgery, it is recommended to actively consult a doctor and carry out standardized treatment under the guidance of a physician.