Levofloxacin hydrochloride should not be used to wipe children’s vulva, as it will disrupt the balance of their vulvar microenvironment and may cause side effects such as arthropathy. 1. Levofloxacin hydrochloride belongs to the quinolone class of drugs, is a broad-spectrum antibacterial drugs, and antibacterial effect is strong, in the prevention and treatment of a variety of bacterial infections in adults, is widely used. Clinically, Levofloxacin is seldom used for topical application. If it is used to apply to the vulva of infants, children or adolescents, it may disrupt the balance of their vulvar microenvironment. 2. Quinolones can cause damage to cartilage cells, so most of these drugs should not be used in infants, children and adolescents under 18 years of age to avoid side effects such as arthropathy. Therefore, levofloxacin hydrochloride should be used under the guidance of a doctor, strictly grasp the indications for the use of the drug, not blindly use the drug, if the child’s vulva shows any discomfort it is recommended to consult a doctor in a timely manner, so as to avoid adverse consequences.