Treatments for patients with necrospermia include medication and surgery to help improve symptoms. 1. Medication: Under the guidance of doctors, anti-inflammatory drugs, antioxidant drugs and drugs to improve cellular energy metabolism, such as azithromycin, coenzyme Q10, vitamin E, vitamin C, adenosine triphosphate and other medications can help eliminate inflammation, improve cellular energy metabolism, so as to improve sperm vitality. 2. Surgical treatment: Surgical options can be chosen according to the specific conditions of patients, for example, patients with vas deferens epididymal tail blockage can undergo vas deferens epididymal anastomosis; if there is a problem of vas deferens obstruction, vas deferens end anastomosis can be done; and patients with ejaculatory duct obstruction can be given urethral ejaculatory ductotomy. 3. Other treatments: For patients with infertility of azoospermia with poor treatment effect, according to the quantity and quality of semen of the male partner, artificial assisted reproduction techniques including artificial insemination and in vitro fertilization-embryo transplantation can be adopted to help them conceive. Necrospermia treatment methods are more diverse, specific also need to be decided according to the patient’s personal situation, it is recommended that patients go to the regular hospital as soon as possible, in the professional doctor’s help in the treatment, do not unauthorized use of medication.