Since hepatitis B is a contagious disease widely spread in the world and there are many people infected with hepatitis B virus, so everyone, especially medical workers, may have accidental contact with the blood of hepatitis B patients in their daily life or at work, so how to deal with the accidental contact with the blood of hepatitis B patients? How to deal with accidental contact with blood of hepatitis B patients? In response to this question, generally speaking, human skin has a barrier function, bacteria and viruses are not suitable to enter the human body, so if the skin is intact when contacted with the blood of hepatitis B patients, rinse it off with soap and water in time; however, if there is a break in the skin when contacted with the blood of hepatitis B patients (especially medical workers), in order to effectively avoid the hepatitis B virus entering into the bloodstream and infecting the human body through the broken parts, the following precautionary measures should be taken in time. Timely take the following preventive measures: 1, the contact person who has not been vaccinated against hepatitis B should be vaccinated against hepatitis B immunoglobulin in a timely manner (within 24h), and then be vaccinated against hepatitis B vaccine according to the 0-1-6 program for the whole course of 3 shots (but it should be noted that the first shot of hepatitis B vaccine should be vaccinated one week after the vaccination of hepatitis B immunoglobulin). 2. Contacts who have been vaccinated with hepatitis B vaccine but have not completed the full immunization should also receive one shot of hepatitis B immunoglobulin in a timely manner (within 24h), and then make up for the full immunization according to the immunization requirements of the full immunization with hepatitis B vaccine (make up for the remaining number of shots). 3.Completing the full immunization of hepatitis B vaccine and producing hepatitis B protective antibodies for the contacts, the level of hepatitis B antibody titer should be determined according to the level of hepatitis B antibody in the body: if the level of hepatitis B antibody is higher (titer above 10 units), there is no need to deal with it; if the level of hepatitis B antibody is weaker, it should be strengthened with a shot of hepatitis B vaccine; however, for the poor immunity of the organism (initial vaccination against hepatitis B vaccine does not respond), it should be vaccinated early with 1 shot of hepatitis B immune globulin and 1 shot of hepatitis B vaccine each. Globulin and hepatitis B vaccine 1 injection each. However, it should be noted that: even for those who are accidentally exposed to the blood of hepatitis B patients and reasonably treated according to the above requirements, blood should be drawn after 6 months to review hepatitis B markers, in order to observe the effect of the treatment and find out the abnormality in time.