How to properly understand hepatitis B

On April 30, a news that Wu Xinyi, a freshman student in the College of Elementary Education of Tianjin Normal University, was discriminated against and isolated for being a hepatitis B virus carrier and then burned charcoal to commit suicide, made everyone regret the death of this young life, and this incident made the social problem of hepatitis B discrimination once again attract wide public attention. In fact, the discrimination against hepatitis B in society stems from fear, and fear stems from ignorance. Only by eliminating misunderstandings in awareness can we avoid regrets in reality. We have analyzed some of the “rumors” about hepatitis B that have become popular in society over the years. Rumor 1: Hepatitis B virus can be spread through daily contact According to media reports, the deceased’s roommates knew about her infection and did not dare to touch her coat hangers, her cell phone on other people’s desks, and everyone would put their things away in a hurry. The idea that daily contact such as eating together and shaking hands can transmit hepatitis B is one of the most widely circulated in society. In fact there are viral and non-viral hepatitis. There are five types of viral hepatitis that have been identified: hepatitis A, B, C, D and E. Hepatitis A and E are transmitted through the digestive tract, while hepatitis B, C and D are transmitted vertically from mother to child, through blood, body fluids, injections and sexual contact. Daily work or life contact, such as working in the same office (including sharing office supplies such as computers), shaking hands, hugging, living in the same dormitory, eating together, sharing toilets and other non-blood-exposed contacts are generally not transmitted. This is also the basis for the introduction of the state on the entry physical examination no longer check the indicators related to hepatitis B. The non-viral hepatitis such as drug-related hepatitis, autoimmune hepatitis is not contagious. Rumor 2: I am just a carrier of hepatitis B virus, there is no need to see a doctor. In clinical work, we often see patients who are first diagnosed with cirrhosis or liver cancer, and we find that these people know they are carriers of hepatitis B virus, but usually they do not have regular medical checkups because they “do not feel anything abnormal”, and often they feel discomfort (bloating, abdominal pain, etc.) before coming to the doctor. The patient is often found to be at an advanced stage of the disease, which is a great pity. Because chronic hepatitis B and C often quietly cause liver cell damage, fibrosis and even cirrhosis, liver cancer, so once found to have hepatitis B or C virus infection, we must regularly (3-6 months) to the hospital to check liver function, virology and tumor-related indicators, in order to early detection of changes in the disease, timely treatment. Rumor 3: Hepatitis B is an incurable disease Many hepatitis B patients start to worry and even lose confidence in life once they know they have hepatitis B. In fact, hepatitis B is not a terrible disease. In fact, hepatitis B is not terrible, as long as you believe in science, adhere to the regular long-term treatment, maintain a positive and objective attitude, the majority of patients can get good control of the disease, and can study, work and live normally (including marriage, childbirth). But the majority of patients should also be soberly aware that hepatitis B, like many chronic diseases, is also a chronic, long-term, progressive disease, for most chronic diseases, the current level of medical treatment is not the pursuit of the goal of a cure, but the pursuit of maximum control of the disease, to minimize the impact of chronic diseases on the lives of patients and life. The first thing you need to do is to get rid of the virus by taking a shot of hepatitis B. Some unscrupulous medical institutions have taken advantage of the eagerness of hepatitis B patients and virus carriers to seek treatment, and have been playing “package turn” and “package cure” advertisements. “The result of believing in these rumors is inevitably to be duped and cheated, not only spending money, but more importantly, delaying the time of treatment, and in serious cases, endangering lives. The so-called “turn negative” in the advertisement actually means “DNA turn negative”. In fact, in the regular hospital application of antiviral drugs to obtain HBV DNA undetectable (the so-called turn negative) is still relatively high probability. However, because the existing international drugs are not yet able to act on the “root” of viral replication, most patients need long-term antiviral treatment, it is impossible to remove the “root” with one or three injections. Some patients who have achieved a negative “surface antigen” on treatment have usually been on treatment for a longer period of time (several years). Therefore, it is best to go to a regular hospital for scientific examination and treatment in order to accurately treat the “negative”. The so-called “Big Three” is a positive HBSAg, HBeAg and anti-HBc in the five hepatitis B items; The “small three positive” refers to the hepatitis B five HBsAg, anti-HBe and anti-HBc three positive (the difference is HBeAg and anti-HBe which is positive). Chronic hepatitis B disease depends on the importance of liver function and other indicators; the size of infectiousness depends on the viral load in the blood. After the HBVDNA is undetectable in antiviral therapy, if it is accompanied by a major triplet into a minor triplet, it indicates that the virus is being cleared, but if the HBVDNA is still positive, there is still viral activity even if it has become a minor triplet. Therefore, it is necessary to look at the “major triplet” and “minor triplet” in a dialectical manner according to different times, there is no good or bad. The actual fact is that you will be able to get a lot more than just a few of the most popular and popular products. The fact that the HBV-DNA turns negative is only proof that the treatment is effective, regardless of whether it is interferon therapy or nucleoside therapy, while stopping the medication is another criterion. The patient is generally advised to use interferon for about a year, according to the patient’s efficacy of treatment to determine whether to continue treatment or switch to other programs of treatment, not to stop the drug at will, in order to reduce the relapse of the disease. The duration of nucleoside therapy is much longer. One concern is the recurrence or even aggravation of hepatitis caused by discontinuation of medication. Therefore, for chronic hepatitis B, it is important to use nucleoside (acid) analogs regularly in treatment and not to discontinue them at will. For patients with cirrhosis, especially in the end stage, only nucleoside (acid) analogs can be used for antiviral treatment, and it is recommended to take the drug for life. Rumor 7: Having hepatitis B is equal to having liver cancer If hepatitis B is not treated in time, it is likely to deteriorate and eventually become liver cancer, but not all hepatitis B will develop into liver cancer, only recurrent chronic hepatitis will develop into cirrhosis under certain circumstances, and among patients with cirrhosis, 20-30% of them will malign into liver cancer. Rumor 8: Hepatitis B is hereditary and cannot be married or have children Chronic hepatitis B is an infectious disease and not a hereditary disease. Male carriers are basically unaffected when they have children. Female carriers can have healthy babies if they undergo mother-to-child blocking technology, which allows more than 95 percent of hepatitis B carriers to have healthy babies. Even hepatitis B patients can control their disease through treatment and get married and have children when their liver function is stable and the virus is not replicating. But always remember to consult and consult with an obstetrics and gynecology and liver disease specialist. There is also a social myth that since the mother-to-be’s birth secretions and blood contain the hepatitis B virus, the baby will not be infected with the hepatitis B virus if a cesarean section is used to avoid these, but this idea is completely wrong. Because a cesarean delivery is a surgery that causes bleeding, it is impossible to talk about the baby not being exposed to the mother’s blood. Medical studies have proven that cesarean delivery does not reduce the probability of vertical transmission of hepatitis B. The former State Ministry of Health issued documents back in 2007 and 2010, clearly stating that hepatitis B carriers should not be denied entry to jobs or schools, which shows that hepatitis B carriers are not terrible and should not be discriminated against and isolated. After so many years, these hepatitis B “rumors” are still “poisoning”, even college students with higher education can not escape the nightmare of hepatitis B discrimination, indicating that the road to eliminate hepatitis B discrimination is long. It is necessary for the state to continue to introduce various measures, but also need the media to give strength in publicity, so that the public can get the correct knowledge of prevention and treatment, and to shatter these “rumors” and “distortions” of hepatitis B. At the same time, she also hopes that all units will strengthen the concept of the legal system and stop the unfair treatment of hepatitis B carriers, so that the tragedy of Wu Xinyi will not be repeated.