Gallstones are the most common cause of biliary colic, and some other rare bile duct roundworms, bile duct cancer and cholecystitis can also cause biliary colic. After the emergence of biliary colic need to pay attention to some diseases, mainly to reduce the occurrence of biliary colic with etiological treatment for a clear diagnosis, recurrent pain can be considered for surgical treatment. 1, in the case of a clear cause can be applied to some analgesic, antispasmodic drugs to quickly control biliary colic, especially in patients with acute pain. Generally speaking, the mechanism of biliary colic is mainly due to spasm of biliary smooth muscle caused by stones, inflammation or bile duct obstruction. Characteristically, the pain is more intense. The use of antispasmodic drugs can temporarily relieve the biliary smooth muscle spasm and control the pain. These are drugs that can quickly give relief from the pain. Preferred antispasmodic drugs, such as atropine and scopolamine. 2, paravertebral nerve block is also an effective means of treating biliary colic. 3, Gallstones, frequent attacks of cholecystitis and bile duct cancer should be treated surgically to solve the problem. Frequent attacks of gallstones and cholecystitis can lead to frequent attacks of biliary colic, which can seriously affect the patient’s quality of life, and these causes can lead to a large degree of loss of gallbladder function, so surgery is necessary, and surgery is mainly for gallbladder removal. In general, biliary colic caused by biliary obstruction should be treated surgically as soon as the attack occurs, and this condition can lead to jaundice and liver function damage, which should be treated surgically as soon as it is diagnosed. Although bile duct cancer is also relatively rare at present, it is also one of the causes of biliary colic, and the most effective treatment for this disease is still surgery. After the occurrence of biliary colic, the cause of the occurrence needs to be diagnosed and the prevention is alleviated mainly through treatment of the cause.