Variable angina treatment is appropriate to use the first choice is the conventional anti-angina drugs are: 1, anti-platelet aggregation class of drugs: aspirin enteric soluble tablets oral 100mg 1 tablet / time 1 time / day, clopidogrel tablets oral 75mg 1 time / day; 2, lipid regulating and stabilizing plaque class of drugs: such as atorvastatin, rasulvastatin class of drugs taken orally every night; 3, is a beta-blocker: such as metoprolol extended release tablets 47.5mg 1 time/day, used to reduce myocardial oxygen consumption; 4, vasodilators: nitrates, dilate coronary arteries to improve symptoms; 5, trimetazidine to improve myocardial energy metabolism and prevent angina attacks. In addition to the above drugs to improve symptoms, prognosis and quality of life, because variant angina is usually caused by coronary spasm, non-dihydropyridine calcium channel blockers can also be chosen to relieve coronary spasm, such as diltiazem.