Pituitary-like cysts and pituitary tumors are both caused by the development of abnormal structures in the pituitary gland. The differences between the two are mainly as follows: First, the origins are different. Pituitary cysts generally originate from the bursa of Lacerta, whereas pituitary tumors generally originate from the anterior and posterior pituitary lobes and the remnants of the craniopharyngeal canal. The incidence of pituitary-like cysts is relatively low, accounting for about 10%-20% of lesions in the pituitary gland, while pituitary tumors account for 80% and above. Clinical manifestations are different. Both of them can show symptoms of compression while growing up, such as headache, vision and vision changes, but the endocrine function of pituitary gland is affected differently. Cysts have no secretory function of simply compressing pituitary gland, which leads to endocrine disorder, while pituitary tumors mostly have secretory function and can secrete some hormones such as prolactin. It can make patients appear amenorrhea, lactation, hirsutism, acromegaly and other manifestations. On the other hand, pituitary tumor shows low signal on T1 and high signal on T2, and there is no enhancement on MRI or CT enhancement, and there is no calcification in general. V. Treatment and prognosis are different. Lachrymal cysts generally have good surgical results, are not easy to recur after surgery and have high safety, while pituitary tumors are more risky after surgery and still need to be treated with radiotherapy after surgery and require some oral hormonal drugs to help recovery.