Gallstones are a common disease in our daily life and a common occurrence. What is the best case for gallstones surgery? Gallstones are collectively referred to as gallbladder stones and common bile duct stones. Because gallstones can induce serious complications such as acute cholecystitis, acute cholangitis, and even acute pancreatitis. Therefore, once gallstones are detected by ultrasound, there is an indication for surgical treatment. This is not directly related to the size of the stone, not that large gallstones should be treated surgically, while small gallstones should be treated conservatively. Such a view is wrong. This is because sometimes small stones lead to more serious complications. We all know that the gallbladder is connected to the cystic duct, and the cystic duct and the common hepatic duct converge to inject the common bile duct. The end of the common bile duct is very thin, usually only 2-3 mm, so very small stones are easy to fall from the gallbladder into the end of the common bile duct, forming secondary common bile duct stones and embedment, inducing acute pancreatitis. On the contrary, larger stones cannot be discharged from the gallbladder. The formation of bile duct stones can be avoided. From this point of view, larger stones are instead safer than smaller ones. Of course, there are many patients who have had gallstones for many years in clinical practice, but do not have any uncomfortable symptoms. For such asymptomatic gallstones, surgery is also recommended. Because clinical research has found that gallbladder stones and gallbladder cancer are closely related, 80% of gallbladder cancer patients have gallstones in combination.