The emergence of resistance to antibiotics is not necessarily a lifelong resistance and may change. Antibiotic resistance occurs mainly due to a decrease in the efficacy of the drug after long-term contact between the pathogenic bacteria and the antibiotic, in addition to the structural changes that occur in some pathogenic bacteria that lead to the emergence of drug resistance. However, with the passage of time, the sensitivity of human beings to antibiotics will gradually be restored. Therefore, antibiotic resistance is generally a phase, not permanent. If the resistant antibiotic is not used for a long time, the body will gradually regain its sensitivity to the antibiotic. Antibiotic resistance is currently a medical problem, the use of antibiotics need to be under the guidance of a doctor to use regularly, do not abuse, or may induce the emergence of drug resistance.