There is a relationship between neurasthenia and mood, and neurasthenia and mood go hand in hand. Some neurasthenia can cause a very low mood, while others manifest as a very anxious, irritable and unstable mood. Neurosis is mainly related to the release of neurotransmitters in the brain, such as dopamine, norepinephrine and 5-hydroxytryptamine, and the imbalance in the release of these neurotransmitters. Neurosis is also related to personality traits, for example, some people are naturally sensitive and suspicious, and when they encounter a major stressful event, they will easily develop neurosis. The manifestations of neurasthenia include depression and anxiety. Patients with depression may suffer from lack of sleep, depressed mood and laziness. Anxiety manifestations may appear excessive worry, fear, and also have panic, chest tightness and other somatization symptoms, so the neurological weakness and mood is related.